Formulas of Integration of Permissivity and of Directed Molecular Targeting In Oncogenesis

Lawrence M Agius
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Lawrence M Agius: Department of pathology, University Of Malta Medical School, Malta,

Cancer Therapy & Oncology International Journal, 2018, vol. 8, issue 5, 90-93

Abstract: Dimensions of non-resolution or paradoxically of resolved integrative action allow for a dualized context of constitutive receptor activity and of permissiveness in the creation of the malignant phenotype of cancer cells. The proposition for such permissiveness is compounded by resolved end-result in oncogenesis that is projected in terms of aberrant over-activity of tyrosine kinases that include dimensions of over-activity in the face of non-resolved dynamics of spread and metastasis. It is within such dimensional context that the oncogenesis is portrayed as established pathways within a permissive context for further change progression. Growth factors and transcription factors allow for such permissiveness to integrate with the directed targeting of molecules in terms of protein-protein interactivity and tyrosine kinase formulations.

Keywords: juniper publishers:oncology journals; oncology research journals; oncology journal articles; oncology and cancer case reports; oncology journal of clinical and experimental cancer research; open access; open access journals; Oncology International Journal; juniper publishers reivew (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jctoij:v:8:y:2018:i:5:p:90-93

DOI: 10.19080/CTOIJ.2018.08.555749

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