Metformin and Prostate Cancer: A New Era of Prostate Cancer Research

Bader A Abdelmaksoud
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Bader A Abdelmaksoud: Department of clinical oncology and nuclear medicine, Zagazig University, Egypt

Cancer Therapy & Oncology International Journal, 2018, vol. 9, issue 4, 133-134

Abstract: Metformin, a biguanide, is primary used in the treatment of type 2 diabetes mellitus (T2DM). Recently, there is a growing interest to examine its role in treatment of different types of cancers [1]. Franciosi and colleagues found a reduction in the risk of development of any cancer due to Metformin use in individuals with T2DM in their systematic review; also, other three systematic reviews assessed the effects of Metformin in individuals with any type of cancer. In meta-analysis of other 20 studies for individuals with T2DM showed that Metformin was associated with a 34% reduction in overall mortality and a 38% reduction in cancer-specific mortality.

Keywords: juniper publishers:oncology journals; oncology research journals; oncology journal articles; oncology and cancer case reports; oncology journal of clinical and experimental cancer research; open access; open access journals; Oncology International Journal; juniper publishers reivew (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jctoij:v:9:y:2018:i:4:p:133-134

DOI: 10.19080/CTOIJ.2018.09.555774

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