Dienogest in the Treatment of Endometriosis

Kazushige Adachi, Akiko Otake and Yoshimitsu Yamamoto
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Yoshimitsu Yamamoto: Department of Obstetrics and Gynecology, Minoh City Hospital, Japan

Global Journal of Reproductive Medicine, 2017, vol. 2, issue 3, 41-43

Abstract: Endometriosis is a prevalent chronic disease in up to 10% of women of reproductive age and often causes pain symptoms. In some patients, these symptoms negatively affect quality of life for a long time. Dienogest is an oral progestin that was recently approved for the treatment of endometriosis. It is allowed for long-term administration with a favorable safety and tolerability profile. Dienogest 2mg/day was superior to placebo in relieving pain symptoms in patients with endometriosis, equivalently effective to gonadotropin releasing hormone agonist (GnRHa). The size of endometriomas was reduced by use of dienogest. Postoperative administration of dienogest showed the efficacy in relieving pain and suppressing recurrence of endometrioma in patients with endometriosis. Dienogest was also effective in relieving symptoms in women with deep infiltrating endometriosis (DIE) or extragenital endometriosis. Dienogest is an alternative for the treatment of endometriosis because of its efficacy, safety and tolerability.

Keywords: Journal of Reproductive Medicine; Reproductive Medicine; journal of reproductive medicine; reproductive medicine articles; reproductive medicine articles impact factor; reproductive medicine research journals; reproductive journals list; open access; juniper publishers journals; juniper publishers reivew (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jgjorm:v:2:y:2017:i:3:p:41-43

DOI: 10.19080/GJORM.2017.02.555586

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