Polyol Pathway Shed Light on Non-Obstructive Azoospermia Testicular Sperm Extraction (TESE) Negative ROS Imbalance

Kambiz Gilany
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Kambiz Gilany: Reproductive Biotechnology Research Center, Avicenna Research Institute, Iran

Global Journal of Reproductive Medicine, 2018, vol. 5, issue 5, 96-97

Abstract: In our recent study regarding non-obstructive azoospermia by metabolomics technology, we clearly demonstrated that testicular sperm extraction negative patients are in extreme oxidative imbalance. With a reanalysis of our data and the integration of proteomics data, we found the Polyol pathway is up-regulated in non-obstructive azoospermia testicular sperm extraction negative patients. In this regard, we suggest the contribution of this biochemical pathway in the extreme oxidative imbalance of non-obstructive azoospermia testicular sperm extraction negative patients.

Keywords: Journal of Reproductive Medicine; Reproductive Medicine; journal of reproductive medicine; reproductive medicine articles; reproductive medicine articles impact factor; reproductive medicine research journals; reproductive journals list; open access; juniper publishers journals; juniper publishers reivew (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jgjorm:v:5:y:2018:i:5:p:96-97

DOI: 10.19080/GJORM.2018.05.555675

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