C-Peptide-Boon or Bane in Diabetes

Eerike M, Konda Vgr and Rajamanickam Mk
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Rajamanickam Mk: Department of Pharmacology, Chettinad Hospital & Research Institute, India

Global Journal of Pharmacy & Pharmaceutical Sciences, 2017, vol. 2, issue 1, 12-14

Abstract: Chronic hyperglycemia in diabetes will produce microvascualr & macrovascular complications. Strict glycemic control can reduce but not completely prevent the microvascular complications. C-peptide, a connecting peptide is one of the drugs under clinical trials for treatment of diabetic complications. Previously C-peptide was considered as a byproduct of insulin synthesis, but now it has been proven, as an active hormone with various actions. Replacement with C-peptide has been proven to reduce the type-1 diabetic complications but not in type 2 diabetic complications. This review is focusing on mechanism of action and actions of C-peptide, its role in type1 & type 2 diabetic complications, clinical trials related to C-peptide has been discussed.

Keywords: juniper publishers:Journal of Pharmacy; Global Journal of Pharmacy; Pharmaceutical Sciences; Pharmacy & Pharmaceutical Sciences; pharmaceutical sciences journals; omics online; open access; drug discovery; Clinical Trials; juniper publishers open access journals; juniper publishers reivew (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jgjpps:v:2:y:2017:i:1:p:12-14

DOI: 10.19080/GJPPS.2017.02.555578

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