Systemic Lupus Erythematous Emergence in a Multiple Sclerosis Patient Treated with Fingolimod

Amir Neshatfar
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Amir Neshatfar: Multiple Sclerosis and Neuro-Immunology Research Center, Isfahan University of medical sciences, Iran

Global Journal of Pharmacy & Pharmaceutical Sciences, 2017, vol. 2, issue 5, 110-112

Abstract: Fingolimod (FIN) is a novel therapy in multiple sclerosis with some side effects. There have been some studies in which the potential risk of consequent exacerbation of autoimmune diseases after use of fingolimod has been discussed. According to our knowledge our study is the only one investigating a case of fingolimod causing systemic lupus erythematous. We report a case of multiple sclerosis with no history of any rheumatologic disorder who experienced arthritis within two weeks after initiation of fingolimod therapy, which can be a potential consequence of dysregulation of immune system and its impact on regulatory T cells. Finally we concluded that fingolimod therapy can potentially cause autoimmune disorders in patients with clear history of such diseases.

Keywords: juniper publishers:Journal of Pharmacy; Global Journal of Pharmacy; Pharmaceutical Sciences; Pharmacy & Pharmaceutical Sciences; pharmaceutical sciences journals; omics online; open access; drug discovery; Clinical Trials; juniper publishers open access journals; juniper publishers reivew (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jgjpps:v:2:y:2017:i:5:p:110-112

DOI: 10.19080/GJPPS.2017.02.555600

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