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Chagas Disease: A Neglected Disease

Mohemmed Faraz Khan, Wasim Akhtar, Mohammad Shaquiquzzaman, Garima Verma, Mohammad Mumtaz Alam, Sarwat Tauhid and Syed Rashiduddin
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Mohammad Mumtaz Alam: Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, India
Syed Rashiduddin: Department of Chemistry, Oriental College, India

Global Journal of Pharmacy & Pharmaceutical Sciences, 2017, vol. 3, issue 3, 55-57

Abstract: Chagas disease or American trypanosomiasis is a neglected disease caused by Trypanosoma cruzi and spread by insects ‘triatomine’ or ‘kissing bugs’. Once, this disease was completely confined to the region of Latin America, but has now spread to different regions of the world due to immigration. Around 6 to 7 million people across the world are affected with this infection. This disease presents itself in two phases: acute and chronic, each with its own characteristic features. Various diagnostic techniques are available to confirm this infection. Benznidazole and nifurtimox are clinically used to relive the infected patients. Both these have 100% efficacy, if given soon after infection at the onset of acute phase. However, both of them are associated with some limitations, thereby necessitating the need for novel and safe agents.

Keywords: juniper publishers:Journal of Pharmacy; Global Journal of Pharmacy; Pharmaceutical Sciences; Pharmacy & Pharmaceutical Sciences; pharmaceutical sciences journals; omics online; open access; drug discovery; Clinical Trials; juniper publishers open access journals; juniper publishers reivew (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jgjpps:v:3:y:2017:i:3:p:55-57

DOI: 10.19080/GJPPS.2017.03.555612

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