Modified Starch and Its Potentials as Excipient in Pharmaceutical Formulations

Khalid Garba Mohammed
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Khalid Garba Mohammed: Department of Pharmaceutics and Pharmaceutical Technology, Bayero University Kano, Nigeria

Novel Approaches in Drug Designing & Development, 2017, vol. 1, issue 1, 1-4

Abstract: Despite its vast commercial value, native starch has some inherent weaknesses when it comes to pharmaceutical application, to mention few include; poor compressibility, low flow ability values and often drug/excipient compatibility problems. In this review, some potentials of modified starch with particular emphasis on their improved functionalities and applicability in pharmaceutical formulations were discussed. Basic requirements for pharmaceutical excipients and various modification methods for starch i.e chemical modification, physical and biotechnological methods were highlighted.Pharmaceutical applications of modified starches as tablet super disintegrant, sustained/ controlled release polymer, plasma volume expanders and as directly compressible excipient in tablet formulations have been cited.

Keywords: juniper publishers; drug designing pdf; drug designing articles; drug designing abstract; drug designing journal; modern approaches in drug designing journal; drug designing & intellectual properties international journal; peer reviewed open access journals; high impact journals; juniper publishers review (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jnapdd:v:1:y:2017:i:1:p:1-4

DOI: 10.19080/NAPDD.2017.01.555551

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