Epigenetic Targets in the Treatment of cancer

Giovanni Codacci-Pisanelli
Additional contact information
Giovanni Codacci-Pisanelli: Department of Medical and Surgical Sciences and Biotechnology, Sapienza University of Rome, Italy

Novel Approaches in Drug Designing & Development, 2017, vol. 1, issue 4, 56-57

Abstract: After the identification of genetic elements in DNA it became apparent that specific cell functions required sophisticated mechanism to regulate gene expression [1]. This is obtained by modifications of DNA and of histones: methyl residues can be inserted on DNA (cytidine) or on histones (lysine or arginine), while acetyl groups on histones are added or removed to turn genes on or off. The epigenetic machinery is very complex consisting of different protein complexes responsible for the different steps required: by applying a simplification that is certainly inaccurate but useful in practical terms, proteins involved in epigenetic regulation can be divided into writers, erasers and readers.

Keywords: juniper publishers; drug designing pdf; drug designing articles; drug designing abstract; drug designing journal; modern approaches in drug designing journal; drug designing & intellectual properties international journal; peer reviewed open access journals; high impact journals; juniper publishers review (search for similar items in EconPapers)
Date: 2017
References: View references in EconPapers View complete reference list from CitEc
Citations:

Downloads: (external link)
https://juniperpublishers.com/napdd/pdf/NAPDD.MS.ID.555567.pdf (application/pdf)
https://juniperpublishers.com/napdd/NAPDD.MS.ID.555567.php (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:adp:jnapdd:v:1:y:2017:i:4:p:56-57

DOI: 10.19080/NAPDD.2017.01.555567

Access Statistics for this article

Novel Approaches in Drug Designing & Development is currently edited by Sophia Mathis

More articles in Novel Approaches in Drug Designing & Development from Juniper Publishers Inc.
Bibliographic data for series maintained by Robert Thomas ().