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Landscaping of Quinoline based Heterocycles as Potential Antimicrobial Agents: A Mini Review

Nisheeth C Desai, Bonny Y Patel, Krunalsinh A Jadeja and Bharti P Dave
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Krunalsinh A Jadeja: Division of Medicinal Chemistry, Department of Chemistry (DST-FIST Sponsored & UGC NON-SAP), Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar-364002, India
Bharti P Dave: Department of Life Sciences, Maharaja Krishnakumarsinhji Bhavnagar University, Bhavnagar, India

Novel Approaches in Drug Designing & Development, 2017, vol. 1, issue 4, 64-67

Abstract: In this mini-review, we have compiled our research group’s prior efforts aimed at developing potential, novel and safe antimicrobial agents with improved efficiency by using the hybrid molecular approach on quinoline hybrids. Present mini-review article deals with landscaping of quinoline based bioactive analogues with pyrazoles, thiazoles, 4-thiazolidinones, pyrimidines and 2-pyridones heterocycles. Quinoline motifs containing hybrids with two or more fold antimicrobial activity are described hereby. We have reported a mini review of 174 compounds prepared in our laboratory. The SAR of the most promising compounds is also discussed.

Keywords: juniper publishers; drug designing pdf; drug designing articles; drug designing abstract; drug designing journal; modern approaches in drug designing journal; drug designing & intellectual properties international journal; peer reviewed open access journals; high impact journals; juniper publishers review (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jnapdd:v:1:y:2017:i:4:p:64-67

DOI: 10.19080/NAPDD.2017.01.555570

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