Annexin 2 Protein Expression is Associated with Breast Cancer Subtypes in African American Women

Desta A Beyene, Norma F Kanarek, Tammey J Naab, Santa L Ricks and Tamaro S Hudson
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Desta A Beyene: Department of Biochemistry and Molecular Biology, Howard University, USA
Norma F Kanarek: Department of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, USA
Tammey J Naab: Department of Pathology, Howard University, USA
Santa L Ricks: Department of Biological Sciences, Hampton University, USA
Tamaro S Hudson: Department of Research, Veteran Affairs Medical Center, USA

Novel Approaches in Drug Designing & Development, 2019, vol. 4, issue 5, 125-133

Abstract: Breast cancer is the most common cancer diagnosis and the second leading cause of death among American women [1]. African American breast cancer patients of all ages are more likely to have advanced disease at diagnosis, an increased risk of recurrence and a poorer prognosis compared with their Caucasian counterparts [2,3]. Tumor stage, tumor grade and lymph node metastasis are commonly used as prognostic factors for breast cancer [4]. However, these are not sufficient for accurately predicting [4]. Therefore, biomarkers are needed to more accurately predict survival outcome. Considering the role of ANX2 in tumorigenesis and metastasis its use as prognostic marker for breast cancer needs to be investigated.

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Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jnapdd:v:4:y:2019:i:5:p:125-133

DOI: 10.19080/NAPDD.2019.04.555650

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