Recent Studies Regarding the Safety and Efficacy of Bitter Orange Extract (P-Synephrine)
Sidney J Stohs,
Sidhartha D Ray and
Howard Miller
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Sidney J Stohs: Creighton University Medical Center, USA
Sidhartha D Ray: Manchester University College of Pharmacy, USA
Howard Miller: Proformance Ingredients, USA
Nutrition & Food Science International Journal, 2018, vol. 7, issue 2, 44-47
Abstract:
Citrus aurantium (bitter orange) extract and its primary protoalkaloidal constituent p-synephrine have been widely used for weight management, appetite suppression, sports performance, energy and focus. Although questions have been raised regarding the safety of p-synephrine, over 30 research studies involving over 700 human subjects as well as animal studies have demonstrated its safety and efficacy. No significant adverse effects were reported in any of these studies. In addition, in vitro studies have provided extensive data regarding the multiple mechanisms of action of bitter orange extract and p-synephrine which acts as a metabolic enhancer and thermogenic agent without cardiovascular stimulant properties.
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Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jnfsij:v:7:y:2018:i:2:p:44-47
DOI: 10.19081/NFSIJ.2018.07.555708
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