Congenital Zika Syndrome A Clinical Study of Six Patients

Orlando J Castejón, Torres Ytalo, Pedro Finol Parra, Patricia Galindez, Maria Salones Castejón and Grundbaum Esmeira
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Grundbaum Esmeira: Department of Neuroscience, Zulia University, Venezuela

Open Access Journal of Neurology & Neurosurgery, 2019, vol. 10, issue 2, 26-30

Abstract: Six infant patients with microcephaly and neurodevelopmental disorders were studied from the clinical point of view exhibiting mainly reduced cephalic circumference, spastic paralysis of upper and lower extremities, ostetendinous hiperreflexia, bilateral strabismus, dysmorphic faciee and genu valgo bilateral. Transfontanelar ecography showed thin and porous aspect of corpus callosum, and ventricolomegaly. Computerized axial tomography showed lissencephaly and calcifications in basal ganglia and dispersed in the thick and condensed brain parenchyma. Nuclear magnetic resonance neuroimages showed ventriculomegaly, absence of corpus callosum, scarce differentiation of gray and white matter, and vascular and cerebellar hypoplasia. Electroencephalographic recording displayed focal paroxysmal activity and hipsarritmia in some patients. Mothers were infected in the first and second trimester of pregnancy.

Keywords: Open Access Journal of Neurology; Journal of Neurology & Neurosurgery; Open Access Journal; juniper publishers; neurology open access journals; journal of neurology; neurology indexed journals; neurology scholarly journals; journal of neurology; neurology journals impact factor; juniper publishers reivew (search for similar items in EconPapers)
Date: 2019
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Persistent link: https://EconPapers.repec.org/RePEc:adp:joajnn:v:10:y:2019:i:2:p:26-30

DOI: 10.19080/OAJNN.2019.10.555782

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