First Time in Human Study: Neuroseal Dural Sealant Prevents Cerebrospinal Fluid Leakage Following Elective Cranial Surgery

Pal Barzo, Sandor Szabo, Peter Orbay and Virginia Jamieson
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Pal Barzo: Department of Neurosurgery, University of Szeged, Albert Szent-Györgi Medical Center, Hungary
Sandor Szabo: Department of Neurosurgery, Medical School University Debrecen, Hungary
Peter Orbay: National Institute of Neurosurgery, Hungary
Virginia Jamieson: Kuros Biosurgery AG, Switzerland

Open Access Journal of Neurology & Neurosurgery, 2020, vol. 12, issue 5, 118-125

Abstract: Cerebrospinal Fluid (CSF) leakage remains a significant cause of morbidity and mortality and can occur when no watertight Dural closure is achieved after neurosurgery. We carried out a retrospective clinical study to investigate the safety and effectiveness of a novel dural sealant, Neuroseal, to stop or prevent CSF leakage following elective cranial surgery. In a prospective, open, multi-center, single-arm study in 45 adult patients (n=38 completed) eligible patients received Neuroseal, a novel, colored synthetic dural sealant to augment dural closure following suturing of the dura.ssss

Keywords: Open Access Journal of Neurology; Journal of Neurology & Neurosurgery; Open Access Journal; juniper publishers; neurology open access journals; journal of neurology; neurology indexed journals; neurology scholarly journals; journal of neurology; neurology journals impact factor; juniper publishers reivew (search for similar items in EconPapers)
Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:adp:joajnn:v:12:y:2020:i:5:p:118-125

DOI: 10.19080/OAJNN.2020.12.555850

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