Embolic Stroke and Nephrotic Syndrome: A Case Report and Literature Review

Nishanth Kodumuri, Sonal Mehta, Charmaine Jenkins, Ravish Kothari and X Michelle Androulakis
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X Michelle Androulakis: Department of Neurology, University of South Carolina School of Medicine, USA

Open Access Journal of Neurology & Neurosurgery, 2017, vol. 2, issue 4, 58-64

Abstract: Nephrotic syndrome (NS) is less commonly associated with arterial thrombosis than venous thrombosis. We report a case of a 43-year-oldwomanwho presented with an acute embolic stroke confirmed on MRI, about 3 months after the diagnosis of NS. The standard stroke evaluations did not show evidence ofcardiac source of embolism, large vessel atherosclerosis or any primary hypercoagulable disorders. Laboratory tests revealed impaired renal function and extremely high nephrotic range proteinuria and a renal biopsy showed primary membranous glomerulonephropathy. Subsequently, she was discharged on anticoagulation and responded well to the treatment. This case illustrates the importance of considering hypercoagulable evaluation due to nephrotic syndrome as a potential cause of embolic stroke, and the initiation of anticoagulation therapy in a timely manner. We also present a literature review on the association between nephrotic syndrome and acute stroke.

Keywords: Open Access Journal of Neurology; Journal of Neurology & Neurosurgery; Open Access Journal; juniper publishers; neurology open access journals; journal of neurology; neurology indexed journals; neurology scholarly journals; journal of neurology; neurology journals impact factor; juniper publishers reivew (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:joajnn:v:2:y:2017:i:4:p:58-64

DOI: 10.19080/OAJNN.2017.02.555591

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