Primary Central Nervous System Lymphoma: A Diagnostic and Therapeutic Challenge-Case Report and Short Review

Adriana Octaviana Dulamea, Ioana Lupescu, Alina Buture, Sorina Badelita and Ioana Lupescu
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Ioana Lupescu: UMF Carol Davila Bucharest, Romania
Alina Buture: Department of Neurology, Fundeni Clinical Institute, Romania
Sorina Badelita: Department of Hematology, Fundeni Clinical Institute, Romania
Ioana Lupescu: Department of Radiology Fundeni Clinical Institute, Romania

Open Access Journal of Neurology & Neurosurgery, 2017, vol. 4, issue 4, 70-73

Abstract: Primary central nervous system lymphoma (PCNSL) is a rare CNS tumor characterized, in immune competent patients, by solitary, homogenous lesions, usually located into the cerebral hemispheres or basal ganglia. Authors report a case of PCNSL with unusual magnetic resonance imaging (MRI) findings, resembling the lesions of acute disseminate encephalomyelitis. New advanced MR imaging techniques such as diffusion, perfusion, MRS may help to differentiate PCNSL from other CNS lesions, for the prognostic, and for treatment response monitoring. PCNSL treatment involves high dose chemotherapy including methotrexate and cytarabine combined with anti-CD20 antibody-based immunotherapy and whole brain radiotherapy

Keywords: Open Access Journal of Neurology; Journal of Neurology & Neurosurgery; Open Access Journal; juniper publishers; neurology open access journals; journal of neurology; neurology indexed journals; neurology scholarly journals; journal of neurology; neurology journals impact factor; juniper publishers reivew (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:joajnn:v:4:y:2017:i:4:p:70-73

DOI: 10.19080/OAJNN.2017.04.555647

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