Neuroprotective Effects of Agmatine and Hippocampal Neuron Loss in the Depression

Meng Yang Zhu
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Meng Yang Zhu: Department of Biomedical Sciences, East Tennessee State University, USA

Open Access Journal of Neurology & Neurosurgery, 2018, vol. 7, issue 5, 105-108

Abstract: Agmatine is anendogenous polyamine and potential neurotransmitter in the brain. This article reviewed the neuroprotective effects of agmatine on hippocampal neurons against glutamate and glucocorticoids-induced neuronal damage. As neuronal loss in the hippocampus is a characteristic of depression, the neuroprotective activity of agmatine may play important role in the pathophysiology of major depression.

Keywords: Open Access Journal of Neurology; Journal of Neurology & Neurosurgery; Open Access Journal; juniper publishers; neurology open access journals; journal of neurology; neurology indexed journals; neurology scholarly journals; journal of neurology; neurology journals impact factor; juniper publishers reivew (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:joajnn:v:7:y:2018:i:5:p:105-108

DOI: 10.19080/OAJNN.2018.07.555725

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