siRNA Delivery Systems in Cancer Therapy

Hossein Hosseinkhani
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Hossein Hosseinkhani: Innovation Center for Advanced Technology, Matrix, USA

Organic & Medicinal Chemistry International Journal, 2020, vol. 10, issue 1, 1-3

Abstract: delivery systems (DDS) have shown great promise in delivery of drugs and genetic materials or pharmaceuticals and other xenobiotics to their site of action within an organism and eliminate the side effect and enhance the therapeutic effects of the drugs at exact delivery position. Small interfering RNA (siRNA) is a class of nucleic acid-based drugs able to suppress gene expression by interaction with mRNA before its translation. The primary success of siRNA delivery greatly depends on suitable vectors to deliver therapeutic genes. The main problems in the delivery of siRNA-based drugs for therapeutic use are the low efficiency of siRNA delivery to target cells and tissues. This review articles discusses the recent technology of siRNA delivery systems using new biomaterials and nanoparticles.

Keywords: juniper publishers:Medicinal Chemistry; Biochemistry Journal; Pharmacology Journal; biochemical pharmacology; molecular pharmacology; biochemistry; open access journals; peer reviewed journals; Open Access; Journal of Molecular Biochemistry; International Research Journal of Pure and Applied Chemistry; World Journal of Biological Chemistry; Biochemistry and Analytical Biochemistry; Biochemistry & Physiology: Open Access; Molecular Biology International; Plant Biochemistry & Physiology; International Journal of Molecular Sciences; Journal of Clinical and Medical Genomics; Environmental Analytical Chemistry; Medicinal Chemistry; Juniper publishers reivews (search for similar items in EconPapers)
Date: 2020
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jomcij:v:10:y:2020:i:1:p:1-3

DOI: 10.19080/OMCIJ.2020.10.555776

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