Pharmaceutical and Biological Effects of Suramin and Potential of Its Derivatives and Analogues
Shwu-Chen Tsay,
Nitesh K. Gupta,
Sergey O Bachurin and
Jih Ru Hwu
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Nitesh K. Gupta: Department of Chemistry, National Tsing Hua University, Taiwan
Jih Ru Hwu: Department of Medical and Biological Chemistry, Institute of Physiologically Active Compounds, Russian Academy of Science, Russia
Organic & Medicinal Chemistry International Journal, 2017, vol. 2, issue 4, 72-76
Abstract:
As a popular drug, suramin has attracted much attention for a century. It has an extensive record of clinical trials. This review article gives a brief introduction of its wide biological roles, remarkable pharmacological activities, and several side effects. Chemists and biological scientists have been working together for the design and synthesis of its derivatives and analogues. Some structure-activity relationships have been realized and provide guidelines for its prosperous development in the near future.
Keywords: juniper publishers:Medicinal Chemistry; Biochemistry Journal; Pharmacology Journal; biochemical pharmacology; molecular pharmacology; biochemistry; open access journals; peer reviewed journals; Open Access; Journal of Molecular Biochemistry; International Research Journal of Pure and Applied Chemistry; World Journal of Biological Chemistry; Biochemistry and Analytical Biochemistry; Biochemistry & Physiology: Open Access; Molecular Biology International; Plant Biochemistry & Physiology; International Journal of Molecular Sciences; Journal of Clinical and Medical Genomics; Environmental Analytical Chemistry; Medicinal Chemistry; Juniper publishers reivews (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jomcij:v:2:y:2017:i:4:p:72-76
DOI: 10.19080/OMCIJ.2017.02.555593
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