Pesticides Induced Infertility Targeting Ovarian Granulosa Cells

Jitender Kumar Bhardwaj and Priyanka Saraf
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Priyanka Saraf: Reproductive Physiology Laboratory, Department of Zoology, Kurukshetra University, India

Organic & Medicinal Chemistry International Journal, 2017, vol. 4, issue 2, 27-30

Abstract: Female infertility is quite common these days, and among numerous causes, pesticides, directly or indirectly, forms an important reason for infertility among individuals. Studies suggest that pesticides modulate ovarian physiology but its’ efficacies on granulosa cells inducing apoptosis determines the follicular fate. This in turn affects the oocyte production and quality. The role of granulosa cells as endocrine cells is significant and any alteration may produce temporary or permanent infertility. The study focuses upon the pesticide induced granulosa cells apoptosis and the probable mechanism associated with it. In addition, potentials of antioxidants in preventing granulosa cells apoptosis have been brought to light that may serve as boon in preventing pesticides induced infertility.

Keywords: juniper publishers:Medicinal Chemistry; Biochemistry Journal; Pharmacology Journal; biochemical pharmacology; molecular pharmacology; biochemistry; open access journals; peer reviewed journals; Open Access; Journal of Molecular Biochemistry; International Research Journal of Pure and Applied Chemistry; World Journal of Biological Chemistry; Biochemistry and Analytical Biochemistry; Biochemistry & Physiology: Open Access; Molecular Biology International; Plant Biochemistry & Physiology; International Journal of Molecular Sciences; Journal of Clinical and Medical Genomics; Environmental Analytical Chemistry; Medicinal Chemistry; Juniper publishers reivews (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jomcij:v:4:y:2017:i:2:p:27-30

DOI: 10.19080/OMCIJ.2017.04.555633

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