Quinolones in Medicinal Chemistry: are Potential Applications Compromised by Limited Synthetic Approaches

Pedro Horta, Alina Secrieru, Andy Coninckx and Maria LS Cristiano
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Andy Coninckx: CCMar - Centro de Ciências do Mar do Algarve, Campus de Gambelas, Universidade do Algarve, Portugal
Maria LS Cristiano: Departamento de Química e Farmácia, FCT, Campus de Gambelas, Universidade do Algarve, Portugal

Organic & Medicinal Chemistry International Journal, 2017, vol. 4, issue 5, 91-93

Abstract: Quinolones (oxoquinolines) belong to the broad family of quinolines, bearing a carbonyl group at any position of the quinoline core [1]. The versatility of the quinolone chemo type attracted the interest of researchers for several decades, leading to a wealth of information that unravelled the potential of quinolones for applications in major fields, namely in medicinal chemistry. Quinolones are nowadays associated to several pharmacological properties, with quinolone derivatives being either used as drugs or under development as drug candidates, to target a variety of human diseases and disorders.

Keywords: juniper publishers:Medicinal Chemistry; Biochemistry Journal; Pharmacology Journal; biochemical pharmacology; molecular pharmacology; biochemistry; open access journals; peer reviewed journals; Open Access; Journal of Molecular Biochemistry; International Research Journal of Pure and Applied Chemistry; World Journal of Biological Chemistry; Biochemistry and Analytical Biochemistry; Biochemistry & Physiology: Open Access; Molecular Biology International; Plant Biochemistry & Physiology; International Journal of Molecular Sciences; Journal of Clinical and Medical Genomics; Environmental Analytical Chemistry; Medicinal Chemistry; Juniper publishers reivews (search for similar items in EconPapers)
Date: 2017
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jomcij:v:4:y:2017:i:5:p:91-93

DOI: 10.19080/OMCIJ.2017.04.555647

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