Synthesis Of 2-Styryl Derivatives of N, N-Bis-Substituted Quinazolines

Harutyunyan Artur A, Ghukasyan Gohar T and Danagulyan Gevorg G
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Harutyunyan Artur A: Russian Armenian (Slavonic) University, Armenia, Asia
Danagulyan Gevorg G: Scientific and technological center of organic and pharmaceutical chemistry, Russian Armenian (Slavonic) University, Armenia, Asia

Organic & Medicinal Chemistry International Journal, 2018, vol. 7, issue 3, 114-114

Abstract: Interest in the heterocyclic quinazoline system is largely due to the high biological activity that they exhibit, including anti protozoic, anti-inflammatory, sedative, antibacterial, as well as the ability to inhibit kinases, the aurora-serine/threonine kinase involved in the regulation of cell division [1]. In recent works, attention has been drawn to the substituted 2-styrylquinazolines, showing antibacterial, fungicidal and cytotoxic properties [2] and bis-quinazolines - inhibitors of the epidermal growth factor receptor (EGFR) [3].

Keywords: juniper publishers:Medicinal Chemistry; Biochemistry Journal; Pharmacology Journal; biochemical pharmacology; molecular pharmacology; biochemistry; open access journals; peer reviewed journals; Open Access; Journal of Molecular Biochemistry; International Research Journal of Pure and Applied Chemistry; World Journal of Biological Chemistry; Biochemistry and Analytical Biochemistry; Biochemistry & Physiology: Open Access; Molecular Biology International; Plant Biochemistry & Physiology; International Journal of Molecular Sciences; Journal of Clinical and Medical Genomics; Environmental Analytical Chemistry; Medicinal Chemistry; Juniper publishers reivews (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jomcij:v:7:y:2018:i:3:p:114-114

DOI: 10.19080/OMCIJ.2018.07.555718

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