New Utilities for Cancer Treatment to Inhibit Tubulin Assembly and Suppressing Microtubule Formation: Research Hypothesis

Divya Shastri and Vinit Raj
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Divya Shastri: Department of Pharmacy, Central University of Rajasthan, India
Vinit Raj: Department of Pharmaceutical sciences, Babasaheb Bhimrao Ambedkar University, India

Organic & Medicinal Chemistry International Journal, 2018, vol. 8, issue 1, 11-12

Abstract: The main objective of present research hypothesis was to give the idea and taking the attention of researcher for tubulin as an anticancer drug target. Inhibiting tubulin by novel lead scaffold may be helpful to treat the cancer with reduced side effect and higher selectivity toward the cancer cells. The present problems with cancer drug have cancer cell resistant and adverse effects. Assisting the solution of this problem, we hypothesized; Pharmacophore based selection for new scaffold may exhibit better binding affinity and selectivity towards the tubulin assembly and suppressing microtubule formation and attenuating the adverse effects and resistant of drug molecules.

Keywords: juniper publishers:Medicinal Chemistry; Biochemistry Journal; Pharmacology Journal; biochemical pharmacology; molecular pharmacology; biochemistry; open access journals; peer reviewed journals; Open Access; Journal of Molecular Biochemistry; International Research Journal of Pure and Applied Chemistry; World Journal of Biological Chemistry; Biochemistry and Analytical Biochemistry; Biochemistry & Physiology: Open Access; Molecular Biology International; Plant Biochemistry & Physiology; International Journal of Molecular Sciences; Journal of Clinical and Medical Genomics; Environmental Analytical Chemistry; Medicinal Chemistry; Juniper publishers reivews (search for similar items in EconPapers)
Date: 2018
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Persistent link: https://EconPapers.repec.org/RePEc:adp:jomcij:v:8:y:2018:i:1:p:11-12

DOI: 10.19080/OMCIJ.2018.08.555727

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