Individualized techniques of Implant Coating with an Antibiotic-loaded, Hydroxyapatite/Calcium sulphate Bone Graft Substitute

Holger Freischmidt, Jonas Armbruster, Gregor Reiter, Paul Alfred Grützner, Lars Helbig and Thorsten Guehring
Additional contact information
Jonas Armbruster: BG Unfallklinik Ludwigshafen, Klinik für Unfallchirurgie und Orthopädie, Ludwig-Guttmann-Strasse 13, 67071 Ludwigshafen, Germany
Paul Alfred Grützner: Clinic for Orthopedics and Trauma Surgery, Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Heidelberg University Hospital, Germany
Thorsten Guehring: Arcus Kliniken Pforzheim, Germany

Orthopedics and Rheumatology Open Access Journals, 2019, vol. 15, issue 3, 65-70

Abstract: The treatment of fracture- or non-union- related infections has persistently been a major challenge for both patients and treating surgeons. With rising aging of patients and increasing comorbidities, combined with the heterogeneity of germs and any number of multi-resistance against standard antibiotics, a successful treatment is increasingly difficult. One potential solution could be a custom-made individualized antibacterial coating of standard implants with a biphasic degradable biocarrier that releases high doses of antibiotics around the bone-implant-interface. Here we describe our technique of coating intramedullary nails, plates and press-fit shoulder endoprostheses which may prevent bacterial adhesion and biofilm formation. So far, there is very limited experience in individual coating of implants in hip or knee endoprostheses to prevent reoccurrence of surgical-site infection. Currently no reports are available for coating of stems of shoulder prosthesis and nails or plates for fracture fixation.

Keywords: journal of orthopaedics; orthopaedics journals impact factor; orthopaedics articles impact factor; scholarly publishing orthopedics journals; juniper publishers opena ccess orthopedics journal; Rheumatology; rheumatology journals impact factor 2018; rheumatology journals impact factor; rheumatology open access journals; juniper publishers review (search for similar items in EconPapers)
Date: 2019
References: Add references at CitEc
Citations:

Downloads: (external link)
https://juniperpublishers.com/oroaj/pdf/OROAJ.MS.ID.555912.pdf (application/pdf)
https://juniperpublishers.com/oroaj/OROAJ.MS.ID.555912.php (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:adp:joroaj:v:15:y:2019:i:3:p:65-70

DOI: 10.19080/OROAJ.2019.15.555912

Access Statistics for this article

Orthopedics and Rheumatology Open Access Journals is currently edited by Sophia Mathis

More articles in Orthopedics and Rheumatology Open Access Journals from Juniper Publishers Inc.
Bibliographic data for series maintained by Robert Thomas ().