Effects of Antibiotics on Haemostatic Parameters during Pregnancy

Amaechi R. A., Turay A. A., Okobi T. J., Usoro E. R. and Ken-Iyevhobu B. A.
Additional contact information
Amaechi R. A.: Haematology Unit, Department of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Edo State, Nigeria
Turay A. A.: Medical Microbiology Unit, Department of Medical Laboratory Science, Ambrose Alli University, Ekpoma, Edo State, Nigeria
Okobi T. J.: Biology Department, Georgetown University, Washington D.C., USA
Usoro E. R.: Department of Biomedical Sciences, Augusta University, Augusta Georgia, USA
Ken-Iyevhobu B. A.: Department of Microbiology, Ambrose Alli University, Ekpoma, Edo State, Nigeria

Journal of Biotechnology Research, 2021, vol. 7, issue 3, 57-62

Abstract: An estimated 50,000 Nigerian women die each year from complications of pregnancy and childbirth, accounting for 10% of global estimates of pregnancy maternal death with about 2% resulting from drug induction. This cross-sectional study sets out to evaluate the Prothrombin time test (PT), activated partial thromboplastin time test (aPTT) Erythrocyte sedimentation rate (ESR), and Platelet count (PC) of pregnant women attending antenatal clinics at Oredo Health Centre in Benin City, Edo State. A total number of 130 subjects comprising 100 pregnant women and 30 non-pregnant women were recruited for the study. Prothrombin time (PT), Activated Partial Thromboplastin Time (APTT), Platelet count and Erythrocyte Sedimentation Rate (ESR) were studied using standard manual methods. The prothrombin time (sec) of the pregnant women 1st trimester (19.12±0.77b), 2nd trimester (19.90±1.02 b) and 3rd trimester (19.66±0.56 b), activated partial thromboplastin time (sec) 1st trimester (44.02±1.17 b), 2nd trimester (47.72±1.47 b) and 3rd trimester (45.88±1.10b), Erythrocyte sedimentation rate (mm/hr) 1st trimester (24.37±3.04 a), 2nd trimester (37.83±4.53 a) and 3rd trimester (43.25±5.24 a) and platelet count (X109/L) 1st trimester (248.29±23.18a), 2nd trimester (236.33±13.84 b) and 3rd trimester (239.10±16.07 a) were significantly higher than the prothrombin time (sec) 16.48±0.81 a, activated partial thromboplastin time (sec) 36.53±1.42 a, ESR (mm/hr) 29.83±4.14 a and platelet count (X109/L) 201±9.54 an of the non-pregnant women (p

Keywords: Antibiotics; Pregnancy; Trimester; Coagulation; PT; APTT. (search for similar items in EconPapers)
Date: 2021
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.arpgweb.com/pdf-files/jbr7(3)57-62.pdf (application/pdf)
https://www.arpgweb.com/journal/16/archive/07-2021/3/7 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:arp:rjbarp:2021:p:57-62

DOI: 10.32861/jbr.73.57.62

Access Statistics for this article

Journal of Biotechnology Research is currently edited by Dr. Ashraf Abd El-Halim El-Sayed

More articles in Journal of Biotechnology Research from Academic Research Publishing Group Rahim Yar Khan 64200, Punjab, Pakistan.
Bibliographic data for series maintained by Managing Editor ().