Cell Malignitation Associated To Chromosome Translocations. Clinical Manifestations in Two Pediatric Patients 46,Xy,T(1;4)(Q11q11) and 46,Xy,T(6;9)(P21;Q34)

Aparicio-Rodríguez Jm, Hurtado-Hernández MdL and Chatelain-Mercado S

Journal of Asian Scientific Research, 2013, vol. 3, issue 4, 403-416

Abstract: The majority of de novo structural chromosome aberrations in fetuses and newborns are considered being of cells of mammals for DNA damage during gametogenesis. 4617 chromosomal studies performed during 19 years (from 1992 to 2011), at Hospital Para El Niño Poblano in México, a total of 1596 patients showe positive for DNA aberrations. Among these studies population, 0.23% (11) chromosome translocations were observed. From this data, two male pediatric patients are described, with 1;4 and 6;9 chromosome translocations. Chromosome changes are classified as structural or numeric alterations respectively, and abnormal cell development has been associated with these two specific chromosomal translocations. The patients in this study were then analyzed and compared both hematological and compared to their clinical features.

Keywords: Chromosome; Karyotype; Leukemia; Numeric and structural chromosome changes (search for similar items in EconPapers)
Date: 2013
References: Add references at CitEc
Citations:

Downloads: (external link)
https://archive.aessweb.com/index.php/5003/article/view/3493/5562 (application/pdf)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:asi:joasrj:v:3:y:2013:i:4:p:403-416:id:3493

Access Statistics for this article

More articles in Journal of Asian Scientific Research from Asian Economic and Social Society
Bibliographic data for series maintained by Robert Allen ().