Complications of Influenza: A Descriptive Study of Hospitalized Patients at the Service of Infectious Diseases, UHC Tirana (2024–2025)

Arben Mino, Edmond Puca, Edmond Puca, Migena Qato, Pellumb Pipero and Najada Como
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Arben Mino: Service of Infectious Diseases, University Hospital Center, Tirana, Albania
Edmond Puca: Service of Infectious Diseases, University Hospital Center, Tirana, Albania
Edmond Puca: Service of Infectious Diseases, University Hospital Center, Tirana, Albania
Migena Qato: Service of Infectious Diseases, University Hospital Center, Tirana, Albania
Pellumb Pipero: Service of Infectious Diseases, University Hospital Center, Tirana, Albania
Najada Como: Service of Infectious Diseases, University Hospital Center, Tirana, Albania Department of Infectious Diseases and Dermatology, Faculty of Medicine, Tirana, Albania

International Journal of Research and Innovation in Social Science, 2025, vol. 9, issue 4, 2313-2316

Abstract: Background: Influenza A is a seasonal viral infection that continues to pose a significant public health burden globally. Objective: This study aimed to investigate the complications associated with laboratory-confirmed Influenza A in hospitalized patients at the Service of Infectious Diseases, University Hospital Center (UHC), Tirana, from December 2024 to February 2025. Methods: We retrospectively analyzed medical records of 32 patients aged 14 years or older with serologically confirmed Influenza A. Demographic data, underlying conditions, clinical complications, and laboratory biomarkers (PCR, neutrophils, monocytes, hepatic and renal markers) were collected. Results: Among the 32 confirmed cases, 15 patients (46.9%) developed complications. Pneumonia was the most frequent complication (9 cases), followed by bronchopneumonia (2), acute bronchitis (2), encephalitis (2), tonsillitis (1), and sepsis (1). The majority of complicated cases were elderly (>60 years) and/or had comorbidities such as hypertension, diabetes, or chronic pulmonary or renal disease. PCR, and neutrophil counts demonstrated high diagnostic specificity. Conclusion: Influenza A can result in severe complications, particularly in elderly and comorbid patients. Early recognition, biomarker-guided diagnosis, and targeted interventions are essential to reduce morbidity and mortality.

Date: 2025
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