Pharmaceutical Formulation and in Vitro Evaluation of Herbal Anti – Fungal Cream

Prerana Sahu, Madhur Soni, Divyansh Sahu, Tanuj Pandey, Gyanesh Kumar Sahu and Harish Sharma
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Prerana Sahu: Rungta college of Pharmaceutical Science and Research, Koha Kurud
Madhur Soni: Rungta Institute of Pharmaceutical Sciences and Research, Kohka Kurud
Divyansh Sahu: Rungta Institute of Pharmaceutical Sciences and Research, Kohka Kurud
Tanuj Pandey: Rungta Institute of Pharmaceutical Sciences, Kohka Kurud
Gyanesh Kumar Sahu: Rungta Institute of Pharmaceutical Sciences and Research, Kohka Kurud
Harish Sharma: School of Pharmacy, Anjaneya University, Raipur

International Journal of Latest Technology in Engineering, Management & Applied Science, 2025, vol. 14, issue 5, 174-181

Abstract: The rising incidence of fungal infections has highlighted the urgent need for treatments that are both effective and safe. Herbal antifungal creams have gained attention as a viable alternative to synthetic products due to their natural composition, reduced side effects, and eco-friendly nature. This research is cantered on the formulation and evaluation of a topical herbal antifungal cream that utilizes plant-derived active ingredients known for their antifungal efficacy. Specifically, neem, aloe vera, and clove oil were chosen for their well-documented activity against fungal pathogens. The cream was developed using a stable emulsion base to ensure smooth texture and ease of application. A series of evaluations—including pH stability, spread ability, and antifungal effectiveness—were carried out to assess the product's overall quality and therapeutic potential. The findings revealed notable antifungal activity, along with desirable physical and chemical characteristics, suggesting that the cream is a promising solution for managing fungal skin infections. This study reinforces the value of herbal-based formulations in dermatological care, while also supporting environmentally sustainable healthcare alternatives.

Date: 2025
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