Magnitude, Diversity and Prevalence of Antibiotic Resistant Bacteria in Pediatric Patients of Coastal Area at Khulna Region, Bangladesh

Bijon Kumar Saha, Ayesha Ashraf, Tushar Alom Sm and Shaila Siddiqua
Additional contact information
Bijon Kumar Saha: Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
Ayesha Ashraf: Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh
Tushar Alom Sm: Department of Microbiology, Khulna Medical College Hospital, Khulna, Bangladesh
Shaila Siddiqua: Assistant Professor, Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna-9208, Bangladesh

International Journal of Research and Scientific Innovation, 2024, vol. 11, issue 15, 713-729

Abstract: Antibiotic resistance is one of the biggest public health challenges around the world. A cross-sectional study was conducted to elucidate the magnitude, diversity and antibiotic resistant pattern of coastal pediatric patients. All isolates were characterized by routine bacterial culture, gram staining and biochemical tests. A total of 120 samples from various body fluids of pediatric patients were taken from 3 hospitals in Khulna city. Data were analysed by Excel 2016 and Graphpad Prism (8.0.2). 81 samples (67.5%) showed positive growth, among which 45 (75%) and 36 (60%) were coastal and non-coastal patient’s sample respectively. Out of 9 identified bacteria, 6 were found in both coastal and non-coastal pediatric patients namely, E.coli, Staphylococcus aureus, Klebsiella spp., Streptococcus spp., Salmonella spp., Pseudomonas spp. whereas, Corynebacterium spp. found only in coastal and Acinetobacter spp., & Shigella spp. were found in only non-coastal pediatric patients. Gram negative bacteria were most prevailed both in coastal (66.7%) and non-coastal (72.2%) patients. Moreover, Urinary Tract Infections (UTIs) were more prevalent at early childhood stage (2-5 years of age) in coastal area whereas, infants (28 days-12 months of age) were more prone to pneumonia in non-coastal area. Antibiotic resistance patterns for 10 commonly prescribed antibiotics through Kirby-Bauer disk diffusion method reveals, most of the bacterial strains showed multidrug resistant (≥ 80%) against 7 and/or more classes of antibiotics. Therefore, it is necessary to reduce the abundant use of antibiotics. Institutional antimicrobial resistance surveillance efforts and use of biogenic nanomaterials and microalgae-based technologies could decrease the occurrence.

Date: 2024
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
https://www.rsisinternational.org/journals/ijrsi/d ... issue-15/713-729.pdf (application/pdf)
https://rsisinternational.org/journals/ijrsi/artic ... a-region-bangladesh/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:bjc:journl:v:11:y:2024:i:15:p:713-729

Access Statistics for this article

International Journal of Research and Scientific Innovation is currently edited by Dr. Renu Malsaria

More articles in International Journal of Research and Scientific Innovation from International Journal of Research and Scientific Innovation (IJRSI)
Bibliographic data for series maintained by Dr. Renu Malsaria ().