Chitosan Based Copper (II) and Cadmium Nanoparticles: Synthesis, Characterization, and Investigation of Antibacterial Activity

Gazi Jahirul Islam, Shaheda Zannah and Md. Mohinuddin
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Gazi Jahirul Islam: Department of Chemistry, University of Barishal, Barishal-8254, Bangladesh
Shaheda Zannah: Department of Pharmacy, Southeast University, Dhaka-1208, Bangladesh
Md. Mohinuddin: Department of Chemistry, University of Barishal, Barishal-8254, Bangladesh

International Journal of Research and Scientific Innovation, 2024, vol. 11, issue 6, 543-561

Abstract: Development of novel antibacterial material has become one of the prominent research topics as because bacteria becoming more and more resistant with time and it becomes difficult to combat against bacteria with existing drug materials. Chitosan, a naturally occurring biopolymer offers a feasible framework for the manufacture of metal nanoparticles, which has naturally enhanced antibacterial properties. In this research, copper (Cu2â º) and cadmium (Cd) nanoparticles (NPs) were synthesized utilizing chitosan as a reducing and stabilizing agent. Chitosan based metal nanoparticles were produced via the solution casting process. The parameters and procedures are different from those used in previous studies. The synthesized nanoparticles were characterized using FTIR, TGA, and SEM analysis. The antibacterial capabilities of these nanoparticles were investigated against different strains of bacteria, which showed, enhanced antibacterial activity. Chi-Cu(II) and Chi-Cd NPs have zones of inhibition 30, 35, 36, 33 mm and 35, 31, 31, 38 mm against Pseudomonas aeruginosa, Salmonella bovismorbificans, Salmonella typhi, and Escherichia coli bacteria respectively. Whereas the standard antibiotic kanamycin has zones of inhibition 22, 22, 20, and 20 mm against those bacteria respectively.

Date: 2024
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