Evaluation of Interleukin-4, Micro-Albumin, and Creatinine in Students Exposed to Short-Term Formalin in Nnewi, Anambra State, Nigeria

Ihim Augustine Chinedu, Ndukwu Judith, Ikwelle Tochukwu Anthony, Patrick Chinedu Obi, Onuora Ifeoma Joy, Romanus Ogai Ogalagu and Collins Uchechukwu Obi
Additional contact information
Ihim Augustine Chinedu: Department of Medical Laboratory Science, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria
Ndukwu Judith: Department of Medical Laboratory Science, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria
Ikwelle Tochukwu Anthony: Department of Medical Laboratory Science, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria
Patrick Chinedu Obi: Department of Internal Medicine, Federal University Teaching Hospital Owerri, Imo State, Nigeria
Onuora Ifeoma Joy: Department of Medical Laboratory science, Faculty of health sciences and technology, Chukwuemeka Odumegwu Ojukwu University Igbariam, Anambra State Nigeria
Romanus Ogai Ogalagu: Department of Biochemistry, Tansian University, Umunya, Anambra State, Nigeria
Collins Uchechukwu Obi: Department of Medical Laboratory Science, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Nigeria

International Journal of Research and Scientific Innovation, 2025, vol. 12, issue 2, 163-170

Abstract: Introduction Formaldehyde is a colorless, strong-smelling gas that is commonly used in various industries, including as a preservative in laboratories. This study evaluated interleukin-4, micro-albumin, and creatinine levels in students exposed to short-term formalin at Nnamdi Azikiwe University, Nnewi. A total of 47 students were recruited aged 18-30 comprising 47 students who were not exposed to formalin as control, and 47 students who were exposed to formalin as test subjects. Sandwich ELISA determined Interleukin-4; creatinine was determined by the Jaffe Slot Alkaline Picrate method; micro-albumin by immuno-turbidimetric assay. Data obtained were analyzed with paired t-test and Pearson correlation coefficient test. There was no significant difference in the levels of interleukin- 4 (87.54±79.38) (pg/ml), creatinine (212.54±210.38),(µmol/l), and micro-albumin (31.88±12.01),(mg/l) of students exposed to formalin compared to the control. (P>0.05). There was a correlation between interleukin-4 levels (r=0.569, p=0.000) in pre- and post-exposure. There was no correlation between creatinine, micro-albumin, and micro-albumin creatinine ratio (p>0.05). The study concluded that there were no observed abnormal changes in the levels of interleukin-4, micro-albumin, and creatinine in students exposed to short-term formalin.

Date: 2025
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.rsisinternational.org/journals/ijrsi/d ... -issue-2/163-170.pdf (application/pdf)
https://rsisinternational.org/journals/ijrsi/artic ... ambra-state-nigeria/ (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:bjc:journl:v:12:y:2025:i:2:p:163-170

Access Statistics for this article

International Journal of Research and Scientific Innovation is currently edited by Dr. Renu Malsaria

More articles in International Journal of Research and Scientific Innovation from International Journal of Research and Scientific Innovation (IJRSI)
Bibliographic data for series maintained by Dr. Renu Malsaria ().