Medication Adherence and Health-Seeking Behaviour in Typhoid Fever Treatment: Insights from Kaduna Metropolis, Nigeria

Sani A. Mohammed, Yusuf Akande, Mohammed N. Danjuma, Aishatu Yusha’u Armiya’u and Sherifat B. Anafi
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Sani A. Mohammed: Department of Clinical Pharmacology and Therapeutics, Kaduna State University, Kaduna, Nigeria.
Yusuf Akande: Grants and Collaborations Office, Federal Neuropsychiatric Hospital, Kaduna, Nigeria.
Mohammed N. Danjuma: Department of Pharmacology and Therapeutics, Ahmadu Bello University Zaria, Nigeria.
Aishatu Yusha’u Armiya’u: Department of Clinical Services, Federal Neuropsychiatric Hospital, Kaduna, Nigeria.
Sherifat B. Anafi: Department of Pharmacology and Therapeutics, Ahmadu Bello University Zaria, Nigeria.

International Journal of Research and Scientific Innovation, 2025, vol. 12, issue 2, 995-1001

Abstract: Medication nonadherence and inconsistent health-seeking behaviors significantly hinder the effective treatment of typhoid fever, particularly in low- and middle-income countries (LMICs) like Nigeria. A cross-sectional survey of 175 respondents revealed significant medication nonadherence, with 88% reporting missed doses, primarily due to forgetfulness and financial constraints. Chemists were the most utilized source of medication (60%), surpassing pharmacies and healthcare centers, while 30% of respondents relied on herbal remedies either exclusively or alongside orthodox medicine. Adherence improved post-hospital visits, with 65.7% reporting no missed doses. These findings underscore the need for targeted interventions, including patient education, regulation of informal healthcare providers, and technology-driven adherence support to enhance treatment outcomes and mitigate antimicrobial resistance.

Date: 2025
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