Synthesis, Characterization and Antibacterial Activity of Schiff Base and its Metal (II) Complexes Derived From 3-Aminophenol and Benzaldehyde

Nasiru Pindiga Yahaya and Muhammad Sani Mukhtar
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Nasiru Pindiga Yahaya: Department of Chemistry Gombe State University
Muhammad Sani Mukhtar: Department of Chemistry Gombe State University

International Journal of Research and Scientific Innovation, 2020, vol. 7, issue 10, 227-231

Abstract: New Schiff base ligand was synthesis via a condensation of the ligands in methanol. The Schiff base were synthesize in 1:2 molar ratio reactions.The complexes have been characterized on the basis of FTIR, electronic spectra, melting points, solubility and molar conductance. The invitro antibacterial activity of the complexes were tested using four bacteria strain; gram negative (Escherichia coli, salmonella typhi) and gram positive (staphylococcus pyogenes and staphylococcus aureus). The complexes were formed in good yield and they have various shades of colors and sharp melting points. The IR results for the HL1 synthesized schiff base revealed bands at 1621cm-1 which shifted to higher frequencies in the metal complexes 1622, 1626 and 1621 cm-1,. The band at 690, 666, 696 cm-1and 593, 549,579 cm-1(HL1), were assigned to (M-N) and (M-O) bands in the spectra of the complexes supporting coordination of Schiff base/ligands to respective metals.The electronic spectral data of the complexes suggest an Octahedral and tetrahedral geometry for all the complexes. The molar conductivity indicates that the synthesized complexes are all non-electrolytes and soluble in protic solvent such as methanol and ethanol. The invitro antibacterial screening of schiff base and its metal complexes showed that they are potential antibacterial agents against the tested microorganisms

Date: 2020
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