Neurodegeneration of Pyramidal Cells and Memory Impairment in the Hippocampus of the Brain of Wistar Rats Exposed to X-Ray

Barilugbene Boobari Akiene, Nunyor Akiene and Lekpa Kingdom David
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Barilugbene Boobari Akiene: Department of Medical Imaging, School of Allied Clinical Science, POGIL College of Health Technology, Ijebu-Ode, Ogun State, Nigeria.
Nunyor Akiene: Department of Medical Imaging, School of Medical Imaging Technology, Rivers State College of Health Science and Management Technology, Port Harcourt, River State, Nigeria.
Lekpa Kingdom David: Department of Anatomy, Faculty of Basic Medical Sciences, University of Port Harcourt, Rivers State, Nigeria

International Journal of Research and Scientific Innovation, 2022, vol. 9, issue 10, 54-58

Abstract: This study investigated the histological changes in the hippocampus of the brain in rats exposed to radiation using a plain x-ray. A total of 20 rats were used for the experiment. The rats were divided into four (4) groups (n=5). Group A is the control group while groups B – D were exposed to radiation (255kv) for a specific duration. Water Morris maze was used to assess the neurobehavioral changes in memory and learning. Histological procedures were carried out to see the changes in the histology of the hippocampus. Results show that there was a significant difference in the time taken for the rats to reach the cemented block between the four groups (F (3, 8) = 6.926, p

Date: 2022
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