Cancer Radiotherapy Based on Attenuation Coefficient

Bibek Koirala, Saddam Husain Dhobi, Kishori Yadav, Jeevan Joyti Nakarmi and Khem Poudyal
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Bibek Koirala: Department of Physics, Patan Multiple Campus, Tribhuvan University, Lalitpur-44700, Nepal Innovative Ghar Nepal, Lalitpur-44700
Saddam Husain Dhobi: Department of Physics, Patan Multiple Campus, Tribhuvan University, Lalitpur-44700, Nepal Robotics Academy of Nepal, Lalitpur-44700, Nepal Innovative Ghar Nepal, Lalitpur-44700
Kishori Yadav: Department of Physics, Patan Multiple Campus, Tribhuvan University, Lalitpur-44700, Nepal Innovative Ghar Nepal, Lalitpur-44700
Jeevan Joyti Nakarmi: Department of Physics, Patan Multiple Campus, Tribhuvan University, Lalitpur-44700, Nepal Innovative Ghar Nepal, Lalitpur-44700
Khem Poudyal: Institute of Engineering, Pulchowk Campus, Tribhuvan University, Lalitpur-44700, Nepal

International Journal of Research and Innovation in Applied Science, 2021, vol. 6, issue 12, 21-24

Abstract: The objective of this work is to select the best chemo-material based on the attenuation coefficient. WinXcom software is used to study the attenuation coefficient of tissue, bone, gold, copper oxygen, water, and mixture. The mixture contains 0.5 fractional weight of gold, 0.3 fractional weight of copper, and 0.2 fractional weight of oxygen. The attenuation coefficient determines the loss of radiation when entering into the medium and loss determines the penetration depth of radiation and damage of materials. The amount of radiation loss when the radiation passes through samples gives the information to select the best chemotherapy materials. Because loss of radiation may be due to absorption, scattering ad emission of electrons from the target. In this work, we consider loss due to the emission of the electron because emitted electrons are used to kill the tumor cell. In this work, the mixture of gold, copper, and oxygen sample has a medium attenuation coefficient that means the emitted electron has the best preformation to kill the cancer cell. This is because the emitted electron has not had enough energy to reach healthy tissue and bone. Therefore, both healthy tissue and bone become safer when the mixture sample is used as a chemo-material instead of a single element. If a single element (Au, Cu, and O) is used as chemo-material for cancer therapy, the energy of electron emitted by Au is greater and it may affect the tissue and bone while the energy emitted from Cu and O has less energy and can’t kill the larger amount of cancer cell. Therefore, if the mixture of chemo-material of gold, copper, and oxygen is better and safer than the individual element to load the tumor for radiotherapy.

Date: 2021
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