Evaluation of the antibacterial and chromatographic activity of the stem bark of Andira Inermis (Cabbage Tree)

Quazim B. Adebisi, Andrew D. Gosomji, Bwede D. Danbok and Emeka Aniobi
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Quazim B. Adebisi: Department of Chemistry, Federal college of Education Pankshin Plateau State, Nigeria
Andrew D. Gosomji: Department of Chemistry, Federal college of Education Pankshin Plateau State, Nigeria
Bwede D. Danbok: Department of Chemistry, Federal college of Education Pankshin Plateau State, Nigeria
Emeka Aniobi: Department of Chemistry, Federal college of Education Pankshin Plateau State, Nigeria

International Journal of Research and Innovation in Applied Science, 2021, vol. 6, issue 7, 08-10

Abstract: Plants have been used for centuries for better health care management of mankind. Modern science is now re-focusing its attention on natural plant therapies as a source of dealing with recent health challenges. The aim of this study focuses on the chromatographic and antibacterial activity of the chloroform and ethyl acetate extracts of Andira Inermis (cabbage tree). The Thin layer chromatography test detected 11 components with retention factors between 0.16 and 0.95 proving the presence of secondary metabolites as phytochemicals present within the plant. Antibacterial effects of these extracts were tested against clinical isolates of bacillus subtilis, Escherichia coli, staphylococcus aureus and Pseudomonas aeruginosa at concentrations of 20, 30 and 40mg/ml. The extracts showed inhibitory effects on the microorganisms with inhibition diameter ranges of 8-18mm. However, the chloroform extract showed greater inhibitory action against staphylococcus aureus at the concentration of 40mg/ml. Therefore, the study justifies the use of Andira inermis as a potential source of antibiotics, and suggests the use of more highly effective organic solvents for its extraction.

Date: 2021
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