Comparative Analysis of Anti-Proliferative Effect of Zingiber Officinale (Ginger) and Solanum Lycopersicum (Tomatoes) on Testosterone-Induced Benign Prostatic Hyperplasia in Male Albino Rats

Chukwu-Eze U.S., Mairiga J.P., Ijeomah A.U., M.O. Enemali, M.C. Ukeagbu, Maiva E.P., S. Kasar and C.r Iwuozor
Additional contact information
Chukwu-Eze U.S.: Biochemistry and Molecular Biology Department, Faculty of Natural and Applied Sciences, Nasarawa State University, Nigeria
Mairiga J.P.: Biochemistry and Molecular Biology Department, Faculty of Natural and Applied Sciences, Nasarawa State University, Nigeria
Ijeomah A.U.: Biochemistry and Molecular Biology Department, Faculty of Natural and Applied Sciences, Nasarawa State University, Nigeria
M.O. Enemali: Department of Applied Biochemistry, Faculty of Biosciences, Nnamdi Azikiwe University, Awka, Nigeria
M.C. Ukeagbu: Department of Biology, Alex Ekwueme Federal University Ndufu-Alike Ikwo, Ebonyi State, Nigeria
Maiva E.P.: Biochemistry and Molecular Biology Department, Faculty of Natural and Applied Sciences, Nasarawa State University, Nigeria
S. Kasar: Biochemistry and Molecular Biology Department, Faculty of Natural and Applied Sciences, Nasarawa State University, Nigeria
C.r Iwuozor: Biochemistry and Molecular Biology Department, Faculty of Natural and Applied Sciences, Nasarawa State University, Nigeria

International Journal of Research and Innovation in Applied Science, 2022, vol. 7, issue 8, 64-70

Abstract: Benign Prostatic Hyperplasia (BPH) is a debilitating condition that enlarges the prostate and surrounding tissues mostly in men in their 50’s. This inflammatory process can lead to uncontrolled passage of urine, incomplete urine flow, dribbling at the end of urine stream, hematuria and inability to ejaculate. Zingiber officinale (Zo) and Solanum lycopersicum (Sl) are known to have anti-proliferative, anti-oxidant, and anti-inflammatory effect on the prostate. A completely randomized experimental design was used for this study. A comparative analysis of the two plant extracts were carried out against the standard drug dutasteride (Brand name: Tamsudart) on male albino rats for 30 days. The animals were grouped into six. Analysis of Prostate Specific Antigen, C-reactive protein, Serum electrolytes, and stress markers such as malondialdehyde were assayed, and the prostate weight checked. The positive control group were slightly elevated p

Date: 2022
References: Add references at CitEc
Citations:

Downloads: (external link)
https://www.rsisinternational.org/journals/ijrias/ ... -7-issue-8/64-70.pdf (application/pdf)
https://www.rsisinternational.org/virtual-library/ ... 051938702.1694191524 (text/html)

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:bjf:journl:v:7:y:2022:i:8:p:64-70

Access Statistics for this article

International Journal of Research and Innovation in Applied Science is currently edited by Dr. Renu Malsaria

More articles in International Journal of Research and Innovation in Applied Science from International Journal of Research and Innovation in Applied Science (IJRIAS)
Bibliographic data for series maintained by Dr. Renu Malsaria ().