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Assessment of the Activity of Creatine Kinase in Rabbits Fed with Extracts of Cocos nucifera Milk, Cocos nucifera Water, Vernonia amygdalina and Prosopis africana

Daikwo M.a, Omattah P.e, Abdullahi H.s, Abdullahi M.h and James G.o
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Daikwo M.a: Department of Biochemistry and Molecular Biology, Nasarawa State University, Keffi-Nigeria
Omattah P.e: Department of Biochemistry, Kogi State University, Anyigba-Nigeria
Abdullahi H.s: Department of Biochemistry and Molecular Biology, Nasarawa State University, Keffi-Nigeria
Abdullahi M.h: Department of Biochemistry and Molecular Biology, Nasarawa State University, Keffi-Nigeria
James G.o: Department of Biochemistry, Federal University of Agriculture, Makurdi-Nigeria

International Journal of Research and Innovation in Applied Science, 2023, vol. 8, issue 9, 39-51

Abstract: Despite more specific and sensitive cardiac biomarkers, creatine kinase isoenzyme creatine kinase-muscle/brain (CK-MB) in serum or plasma is still an important parameter for diagnostics of the origin of CK elevations and for disease monitoring. The aim of this study is to investigate the effect of varying doses of coconut milk, coconut water, Vernonia amygdalina (bitter leaf) and Prosopisafricana on creatine kinase. Fifteen adult male rabbits weighing between 1.5kg-2.5kg were divided into five groups of three rabbits each. Group 1 was the reference/control group which received no extract, while groups 2,3,4 and 5 received 5ml/kg per body weight (b.wt) of coconut milk, coconut water, bitter leaf and P. africana extracts respectively. Results obtained revealed that creatine kinase concentration in group 2 was significantly (p

Date: 2023
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