Evaluation of EBNA-1 (epstein-barr virus nuclear antigen-1) gene prevalence in nasopharyngeal carcinoma in Vietnamese patients

Lao Duc Thuan (), Nguyen Hoang Anh Tuan, Ngo Dong Kha, Thieu Hong Hue, Ho Ta Giap, Nguyen Hai Chau, Nguyen Huu Dung and Le Huyen Ai Thuy
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Lao Duc Thuan: University of Science, Vietnam National University Ho Chi Minh City; Ho Chi Minh City Open University, Vietnam
Nguyen Hoang Anh Tuan: University of Science, Vietnam National University Ho Chi Minh City, Vietnam
Ngo Dong Kha: Ho Chi Minh City Open University, Vietnam
Thieu Hong Hue: Ho Chi Minh City Open University, Vietnam
Ho Ta Giap: Ho Chi Minh City Open University, Vietnam
Nguyen Hai Chau: Ho Chi Minh City Open University, Vietnam
Nguyen Huu Dung: Cho Ray Hospital, Ho Chi Minh City, Vietnam
Le Huyen Ai Thuy: Ho Chi Minh City Open University, Vietnam

HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE - ENGINEERING AND TECHNOLOGY, 2016, vol. 6, issue 1, 3-10

Abstract: This study examined the presence of Epstein-Barr virus (EBV) in nasopharyngeal carcinoma (NPC) based on the detection of EBNA-1 (Epstein-Barr virus nuclear antigen-1) by Polymerase Chain Reaction (PCR), in Vietnamese population. Firstly, we systematically analyzed the mean of percentage weighted of the presence of EBNA-1 in previous relevant studies. Experimentally, 31 nasopharyngeal cancer biopsies and 20 healthy samples were enrolled in current to evaluate the frequency of candidate genes. As the results, the frequency of EBNA-1 was 77.42%, whereas, none of any cases of healthy samples were found to positive to target gene. The p value

Keywords: EBNA-1; Nasopharyngeal carcinoma; Vietnamese population (search for similar items in EconPapers)
Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:bjw:techen:v:6:y:2016:i:1:p:3-10

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