Estimation of Population Attributable Fractions from Fitted Incidence Ratios and Exposure Survey Data, with an Application to Electromagnetic Fields and Childhood Leukemia

Sander Greenland

Biometrics, 2001, vol. 57, issue 1, 182-188

Abstract: Summary. Standard presentations of epidemiological results focus on incidence‐ratio estimates derived from regression models fit to specialized study data. These data are often highly nonrepresentative of populations for which public‐health impacts must be evaluated. Basic methods are provided for interval estimation of attributable fractions from model‐based incidence‐ratio estimates combined with independent survey estimates of the exposure distribution in the target population of interest. These methods are illustrated in estimation of the potential impact of magnetic‐field exposures on childhood leukemia in the United States, based on pooled data from 11 case‐control studies and a U.S. sample survey of magnetic‐field exposures.

Date: 2001
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