Maximum Likelihood Ratio Tests for Comparing the Discriminatory Ability of Biomarkers Subject to Limit of Detection
Albert Vexler,
Aiyi Liu,
Ekaterina Eliseeva and
Enrique F. Schisterman
Biometrics, 2008, vol. 64, issue 3, 895-903
Abstract:
Summary In this article, we consider comparing the areas under correlated receiver operating characteristic (ROC) curves of diagnostic biomarkers whose measurements are subject to a limit of detection (LOD), a source of measurement error from instruments' sensitivity in epidemiological studies. We propose and examine the likelihood ratio tests with operating characteristics that are easily obtained by classical maximum likelihood methodology.
Date: 2008
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https://doi.org/10.1111/j.1541-0420.2007.00941.x
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Persistent link: https://EconPapers.repec.org/RePEc:bla:biomet:v:64:y:2008:i:3:p:895-903
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