Using concepts in literature‐based discovery: Simulating Swanson's Raynaud–fish oil and migraine–magnesium discoveries

Marc Weeber, Henny Klein, Lolkje T.W. de Jong‐van den Berg and Rein Vos

Journal of the American Society for Information Science and Technology, 2001, vol. 52, issue 7, 548-557

Abstract: Literature‐based discovery has resulted in new knowledge. In the biomedical context, Don R. Swanson has generated several literature‐based hypotheses that have been corroborated experimentally and clinically. In this paper, we propose a two‐step model of the discovery process in which hypotheses are generated and subsequently tested. We have implemented this model in a Natural Language Processing system that uses biomedical Unified Medical Language System (UMLS) concepts as its unit of analysis. We use the semantic information that is provided with these concepts as a powerful filter to successfully simulate Swanson's discoveries of connecting Raynaud's disease with fish oil and migraine with a magnesium deficiency.

Date: 2001
References: Add references at CitEc
Citations: View citations in EconPapers (2)

Downloads: (external link)
https://doi.org/10.1002/asi.1104

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:bla:jamist:v:52:y:2001:i:7:p:548-557

Ordering information: This journal article can be ordered from
https://doi.org/10.1002/(ISSN)1532-2890

Access Statistics for this article

More articles in Journal of the American Society for Information Science and Technology from Association for Information Science & Technology
Bibliographic data for series maintained by Wiley Content Delivery ().