A Bayesian Analysis of Some Pharmacological Data Using a Random Coefficient Regression Model

T. J. Sweeting

Journal of the Royal Statistical Society Series C, 1982, vol. 31, issue 3, 205-213

Abstract: Extensive measurements of various haemodynamic functions were taken on a number of dogs under control and drug conditions by researchers at the Midhurst Medical Research Institute, the object being to assess the magnitude of a possible direct pharmacological effect of drug on myocardial oxygen consumption. A random coefficient regression model is adopted, and extensions of currently available results are given which permit a Bayesian analysis of these data. It is further argued that the formulae given in this paper should be generally adopted for fitting models of this type.

Date: 1982
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