 Stereological Analysis of Anisotropic Structures Using Directional StatisticsL. M. Cruz‐Orive, H. Hoppeler, O. Mathieu and E. R. Weibel Journal of the Royal Statistical Society Series C, 1985, vol. 34, issue 1, 14-32 Abstract: Classical stereological methods are based on the assumption of isotropy, either of the structure under study or of the sectioning probe relative to the structure. Thus, with “distribution‐free stereology”, anisotropic structures can be studied only via isotropic uniform random probes, which are often difficult to generate or inefficient in practice. Here we present a parametric approach to model the direction of a randomly chosen line or surface element, whereby length and surface densities can be estimated by probes at fixed and known directions. For the material studied, namely skeletal muscle capillaries, the Dimroth–Watson axial distribution provides a good fit. A maximum likelihood procedure for estimating simultaneously the concentration parameter of the Dimroth–Watson distribution and either the length or the surface density for the structure is described and illustrated with the capillary data. When a particular axial model is known to be satisfactory, a short‐cut estimation method of practical value can be used. Date: 1985 Downloads: (external link) Related works: Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text Persistent link: https://EconPapers.repec.org/RePEc:bla:jorssc:v:34:y:1985:i:1:p:14-32 Ordering information: This journal article can be ordered from Access Statistics for this article Journal of the Royal Statistical Society Series C is currently edited by R. Chandler and P. W. F. Smith More articles in Journal of the Royal Statistical Society Series C from Royal Statistical Society Contact information at EDIRC. |
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