Statistical Evaluation of Pharmacopoeia Weight Variation Tests for Tablets Using a Ratio Statistic

Sukalyan Sengupta

Journal of the Royal Statistical Society Series C, 1988, vol. 37, issue 3, 396-400

Abstract: This paper considers the latest pharmacopoeia weight variation tests and calculates the probabilities of passing such tests using the ratio statistic of the form xi/x̄ where the xi are normally distributed. The probabilities are then compared with those obtained by using the method due to Roberts. Roberts's method leads to underestimates of these probabilities. The results are also used to determine the process conditions to be maintained by a manufacturer to pass the weight variation tests.

Date: 1988
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Persistent link: https://EconPapers.repec.org/RePEc:bla:jorssc:v:37:y:1988:i:3:p:396-400

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