Daily mortality/morbidity and air quality: Using multivariate time series with seasonally varying covariances

Guowen Huang, Patrick E. Brown, Sze Hang Fu and Hwashin Hyun Shin

Journal of the Royal Statistical Society Series C, 2022, vol. 71, issue 1, 148-174

Abstract: We study the associations between daily mortality and short‐term variations in the ambient concentrations of fine particulate matter (PM2.5), nitrogen dioxide (NO2) and ozone (O3) in four cities in Canada. First, a novel multivariate time series model within Bayesian framework is proposed for exposure assessment, where the response is a mixture of Gamma and Half‐Cauchy distributions and the correlations between pollutants vary seasonally. A case‐crossover design and conditional logistic regression model is used to relate exposure to disease data for each city, which then are combined to obtain a global estimate of exposure health effects allowing exposure uncertainty. The results suggest that every 10 ppb increase in O3 is associated with a 3.88% (95% credible interval [CI], 2.5%, 5.18%) increase in all‐cause mortality, a 5.04% (2.84%, 7.43%) increase in circulatory mortality, a 7.87% (2.4%, 12.9%) increase in respiratory mortality, a 0.76% (0.19%, 1.35%) increase in all‐cause morbidity and a 6.6% (0.58%, 12.7%) increase in respiratory morbidity. Similarly, every 10 ppb increase in NO2 is associated with a 2.13% (0.42%, 3.87%) increase in circulatory morbidity. The health impacts of PM2.5 are not found to be present once other pollutants are accounted for.

Date: 2022
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