Antioxidant activity of 2,6-dimethyl-3,5-dialkoxycarbonyl-1,4-dihydropyridines in metal-ion catalyzed lipid peroxidation

G. Tirzitis, D. Tirzite and Z. Hyvonen
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G. Tirzitis: Latvian Institute of Organic Synthesis, Riga, Latvia
D. Tirzite: Latvian Institute of Organic Synthesis, Riga, Latvia
Z. Hyvonen: Latvian Institute of Organic Synthesis, Riga, Latvia

Czech Journal of Food Sciences, 2001, vol. 19, issue 3, 81-84

Abstract: Antioxidants with 1,4-dihydropyridine structure were investigated as a less harmful alternative to synthetic phenolic antioxidants in liposomes under conditions simulating food storage. The antioxidant activities (AOA) of 2,6-dimethyl-3,5-dialkoxycarbonyl-1,4-dihydropyridines possessing various side chain length alkyls (CH3 - C16H33) in ester moiety were tested in transition metal-ion catalyzed liposome peroxidation and compared with AOA of Trolox™ and Probucol™. The compounds with C2H5 - C4H9 residues in the 3,5-position ester moieties exert the most pronounced AOA. The AOA of tested compounds is associated with their ability to incorporate into liposomes.

Keywords: 1; 4-dihydropyridines; antioxidants; metal-ion catalyzed peroxidation (search for similar items in EconPapers)
Date: 2001
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Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlcjf:v:19:y:2001:i:3:id:6581-cjfs

DOI: 10.17221/6581-CJFS

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