Stevioside and rebaudioside A - predominant ent-kaurene diterpene glycosides of therapeutic potential: a review

Ena Gupta, Shalini Purwar, Shanthy Sundaram, Prashasti Tripathi and Gyanendra Rai
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Ena Gupta: Centre for Biotechnology and
Shalini Purwar: Centre for Biotechnology and
Shanthy Sundaram: Centre for Biotechnology and
Prashasti Tripathi: Centre of Food Technology, University of Allahabad, Uttar Pradesh, India
Gyanendra Rai: Centre for Biotechnology and

Czech Journal of Food Sciences, 2016, vol. 34, issue 4, 281-299

Abstract: Stevia rebaudiana (Bertoni) is a Paraguayan perennial herb of the family Asteraceae. The leaves contain a great amount of secondary metabolites with a wide range of important biological activities commonly known as steviol glycosides which differ in their molecular configuration, power of sweetness and their taste profile. Out of various steviol glycosides, the main compounds of interest are diterpenoid glycosides of ent-kaurene type extracted from the leaves of this plant as non-toxic, thermally stable, low-calorie natural sweeteners stevioside and rebaudioside A. These glycosides are a high-quality sugar substitute or dietary supplement with diverse applications in the medicinal world along with the food and beverage industry. This review article is aimed at the chemistry of stevioside and rebaudioside A, possible biosynthetic pathways, their metabolism and acceptable daily intake along with a broad spectrum of pharmacological and therapeutic applications.

Keywords: Stevia rebaudiana; secondary metabolites; therapeutic applications; sweetener (search for similar items in EconPapers)
Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlcjf:v:34:y:2016:i:4:id:335-2015-cjfs

DOI: 10.17221/335/2015-CJFS

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