Appraisal of antioxidant potential and biological studies of bogan bail (Bougainvillea glabra) leaf extracts using different solvents

Muhammad Riaz, Humaira Fatima, Muhammad Misbah ur Rehman, Rahman Qadir, Shabbir Hussain, Abdul Hafeez and Abu Bakar Siddique
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Muhammad Riaz: Institute of Chemistry, Faculty of Sciences, University of Sargodha, Sargodha, Pakistan
Humaira Fatima: Institute of Chemistry, Faculty of Sciences, University of Sargodha, Sargodha, Pakistan
Muhammad Misbah ur Rehman: Department of Chemistry, Faculty of Sciences, University of Lahore, Sargodha, Pakistan
Rahman Qadir: Institute of Chemistry, Faculty of Sciences, University of Sargodha, Sargodha, Pakistan
Shabbir Hussain: Department of Chemistry, Faculty of Basic Sciences, Lahore Garrison University, Lahore, Pakistan
Abdul Hafeez: Institute of Chemistry, Faculty of Sciences, University of Sargodha, Sargodha, Pakistan
Abu Bakar Siddique: Institute of Chemistry, Faculty of Sciences, University of Sargodha, Sargodha, Pakistan

Czech Journal of Food Sciences, 2021, vol. 39, issue 3, 176-180

Abstract: Current research work was performed to evaluate the antioxidant, antidiabetic, thrombolytic, and cytotoxic potential of Bougainvillea glabra leaf extracts with different solvents. Extraction of leaves was carried out by maceration using solvents of various polarity such as n-hexane, chloroform, ethyl acetate, n-butanol, and methanol. The highest values of total phenolic and flavonoid contents were assessed in methanolic extract, such as 58.57% and 29.41%, respectively. Antioxidant potential was measured by DPPH free radical, showing 65.16% scavenging activity in methanolic extract. Similarly, the reducing power of methanolic extract was also measured. Hemolytic activity of B. glabra leaf extracts was evaluated, and maximum percentage lysis was found as 6.86% in chloroform extract. The thrombolytic activity of B. glabra leaf extracts was evaluated against human red blood cells, and the maximum percentage of clot lysis was 59.10% in chloroform extract. Maximum antidiabetic activity (16.20%) was observed in methanolic extract. Overall, the presented results reveal that bogan bail extract is capable of being employed in nutra-pharmaceutical industry.

Keywords: B. glabra; scavenging; thrombolytic; antidiabetic; hemolytic (search for similar items in EconPapers)
Date: 2021
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Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlcjf:v:39:y:2021:i:3:id:273-2020-cjfs

DOI: 10.17221/273/2020-CJFS

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Czech Journal of Food Sciences is currently edited by Ing. Zdeňka Náglová, Ph.D.

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