A frontier approach for the production of enteric soft capsules containing omega-3 fatty acids and probiotics

Hayoung Kim, Won Yeong Bang, Boyoung Choi, Han Bin Lee and Jungwoo Yang
Additional contact information
Hayoung Kim: Ildong Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea
Won Yeong Bang: Ildong Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea
Boyoung Choi: Ildong Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea
Han Bin Lee: Ildong Bioscience, Pyeongtaek-si, Gyeonggi-do, Republic of Korea
Jungwoo Yang: Department of Microbiology, College of Medicine, Dongguk University, Gyeongju, Republic of Korea

Czech Journal of Food Sciences, 2024, vol. 42, issue 2, 127-135

Abstract: The study investigated whether omega-3 fatty acids could promote bacterial growth, acid and bile tolerance, and cell adhesion onto Caco-2 cells to develop a multifunctional enteric soft capsule containing probiotics and omega-3 fatty acids. The probiotic strains used were Enterococcus faecium IDCC 2102 and Bacillus coagulans IDCC 1201. Supplementation with omega-3 fatty acids did not significantly affect the growth and viability of either strain at lower concentrations (i.e. 0.5-1.0 w/w %). In comparison, the adhesion ability to Caco-2 cells of both strains was significantly increased (up to 107.5%). Furthermore, Bacillus coagulans IDCC 1201 [1 × 1010 CFU (colony forming unit) per capsule] contained together with omega-3 fatty acids (600 mg per capsule) in the enteric soft capsules showed a stability of over 95% during 12 months of storage at room temperature, which was similar to that of unencapsulated lyophilised probiotics. Thus, these results indicate that multifunctional food supplements in the form of enteric soft capsules are feasible.

Keywords: Bacillus coagulans; Enterococcus faecium; intestinal adhesion; omega-3 fatty acids; probiotics (search for similar items in EconPapers)
Date: 2024
References: View complete reference list from CitEc
Citations:

Downloads: (external link)
http://cjfs.agriculturejournals.cz/doi/10.17221/181/2023-CJFS.html (text/html)
http://cjfs.agriculturejournals.cz/doi/10.17221/181/2023-CJFS.pdf (application/pdf)
free of charge

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:caa:jnlcjf:v:42:y:2024:i:2:id:181-2023-cjfs

DOI: 10.17221/181/2023-CJFS

Access Statistics for this article

Czech Journal of Food Sciences is currently edited by Ing. Zdeňka Náglová Ph.D.

More articles in Czech Journal of Food Sciences from Czech Academy of Agricultural Sciences
Bibliographic data for series maintained by Ivo Andrle ().